Volume 3 Issue 1

Review Article: Functional Foods Tested In vivo and In vitro as A Complement or Substitution in the Pharmacological Treatment of Diabetes

Mariela Enriquez Acevedo, Ruth E Belmares Cerda*, Rosa M. Rodriguez Jasso, Araceli Loredo Trevino, Carolina Flores Gallegos, Ana V. Charles Rodriguez, Mildred I. M. Flores Verastegui, Mario A. Cruz Hernandez and Garza Juarez Aurora

Diabetes is a chronic multi system disease, which consists of major complications largely influenced by glycemic values [1]. One therapeutic practice for the management of diabetes is by controlling postprandial hyperglycemia, along with changes in the life style, consumption of foods with low GI and consumption of drugs. Oral anti diabetic agents available on the market have benefits in the patient health, but scientific evidence of various long term use drugs states that they may have a wide range of negative effects. Recently, different researchers have been working with natural products called functional foods, or ingredients like plants, probiotics and prebiotics with bioactive compounds, which could be used as a raw material to convert this into a functional food and create a viable option for more powerful and safe anti diabetic therapy. In this review, we present the most current information of functional foods, or ingredients with bioactivity, as well as food with low GI, which could complement, or replace the different treatments in diabetes mellitus, tested in vivo and in vitro. Concluding, the studies presented in this paper, show different alternatives that would improve the patients' nutrition and life quality but there is also required to continue investigating and testing to prove the functionality and improve the health of the population with diabetes.

Cite this Article: Acevedo ME, Belmares Cerda RE, Rodriguez Jasso RM, Trevino AL, Gallegos CF, et al. Functional Foods Tested In vivo and In vitro as A Complement or Substitution in the Pharmacological Treatment of Diabetes. Sci J Food Sc Nutr. 2017; 3(1): 023-033.

Published: 14 October, 2017

Research Article: Sickle Cell Disease (SCD) A Hidden Genetic Disorder can be treated by Comprehensive Therapy: Research Based Approaches

Mohammad Nazrul Islam*

Sickle cell disease is caused by a mutation of hemoglobin-beta gene on chromosome 11. It is due to abnormal hemoglobin molecules - hemoglobin S which is attached to each other and form long, rod-like structures. These structures cause red blood cells to become stiff and form a sickle shape. The shape of red blood cells leading to blockage and progressive damage of vital organs and tissues and representing acute chest syndrome, stroke and priapism [painful, prolonged erection]. Pre-marital, post marital counseling, combined or comprehensive therapy are mandatory to reduce the prevalence and consequences of SCD. Early diagnosis and treatment can prevent the drastic effect of SCD. To increase awareness with information, education and communication system is the cost-effective method of SCD prevention.

Cite this Article: Islam MN. Sickle Cell Disease (SCD) A Hidden Genetic Disorder can be treated by Comprehensive Therapy: Research Based Approaches. Sci J Food Sc Nutr. 2017; 3(1): 018-022.

Published: 27 September 2017

Research Article: Allegory of Gluttony and Lust: Labelling of Food Allergens in Dutch Supermarkets

Floranne Boulogne, Kim Smulders, Jesse Buijink, Charlotte Kik, Angela Markovska, Frans J. van Overveld, Ioanna Paspali, Ana Zupanic and Ger T. Rijkers*

The labelling of prepacked food products with information on 13 allergens on the mandatory European list (gluten containing cereals, crustaceans, eggs, fish, peanuts, soybean, cow's milk, nuts, celery, mustard, sesame seeds, lupine, and mollusks) was investigated in the major supermarket chains in The Netherlands. The label information of products from the leading a brand was compared with that of store brands. In general, store brands provide significantly better information about the presence or absence of specific allergens than the A brands do. This information however is restricted to the allergens on the mandatory European list, because the European labelling policies are based on averages for allergy occurrences in Europe. As such, kiwi fruit, a major top-10 occurring allergen in The Netherlands, is not indicated as mandatory. Therefore the labels may not always reflect the local needs of allergic patients. We may conclude that information for allergic consumers therefore can be improved.
Keywords: Allergens; Food products; Labelling; Leading brands; Netherlands; Regulation; Store brands

Cite this Article: Boulogne F, Smulders K, Buijink J, Kik C, Rijkers GT, et al. Allegory of Gluttony and Lust: Labelling of Food Allergens in Dutch Supermarkets. Sci J Food Sc Nutr. 2017; 3(1): 012-017.

Published: August 26, 2017

Research Article: Physicochemical and Rheological Properties of Complementary Diet from Blends of Maize, African Yam Bean and Pigeon Pea Flour

Omolara R. Oludumila* and Victor N. Enujiugha

Complementary diets were obtained from maize, African yam beans and pigeon pea varied and the effect of physicochemical and pasting properties were evaluated. The blends considered were 90:5:5, 80:10:10 and 70:15:15 for maize, African yam bean and pigeon pea respectively. The blends were compared with 100% maize gruel and a commercial weaning diet, Nutrend. The results showed that the complementary blend with ration 70:15:15 had 24.29% protein, 4.05% ash, and 58.49% carbohydrate while 100% maize (ogi) had 10.52% protein, 4.2% ash and 73.02% carbohydrate in comparism with commercially produced diet, Nutrend, which had 21.64% protein, 3.58% ash and 61.35% carbohydrate. Also in terms of mineral composition, the result of the diet analyzed showed that 100% maize (ogi) had the 16 best pasting properties followed closely by both the diet with the 70:15:15 ratios and the commercially produced diet, Nutrend. Overall the 70:15:15 ratios had better proximate and mineral composition while the 100% maize gruel (ogi) had the best pasting properties which were closely followed by 70:15:15.

Cite this Article: Oludumila OR, Enujiugha VN. Physicochemical and Rheological Properties of Complementary Diet from Blends of Maize, African Yam Bean and Pigeon Pea Flour. SRL Nutr Food Sci. 2017; 3(1): 005-011.

Published: June 10, 2017

Short Communication: Grape Juice, Red Wine, Resveratrol and Exercise, In the Expression of FNDC5 and UCP2 in Cardiac and Skeletal Muscles of Wistar Rats Submitted To High-Fat Diet

Raiza da SF. Fiochi*, Leticia MF Cardoso, Nina da MA. Pimenta, Bruna F. Mota, Juliana AS Monnerat, Isabelle Waleska SM. Silva, Vilma B. Azeredo, Adenilson D. Fonseca, Gilson T. Boaventura, Sergio G. Barroso and Gabrielle S. Rocha

Introduction: Diets high fat can lead to obesity and chronic non-communicable diseases. Genes related to thermogenesis regulation may be a possibilty to obesity and its comorbidities prevention.
Objective: Evaluate grape juice, red wine and resveratrol and exercise effects, in gene expression modulation of FNDC5 and UCP2 in cardiac (CM) and skeletal (SM) muscles of Wistar rats.
Introduction: Diets high fat can lead to obesity and chronic non-communicable diseases. Genes related to thermogenesis regulation may be a possibilty to obesity and its comorbidities prevention. Objective: Evaluate grape juice, red wine and resveratrol and exercise effects, in gene expression modulation of FNDC5 and UCP2 in cardiac (CM) and skeletal (SM) muscles of Wistar rats. Method: Rats Wistar, 90 days, 230g, divided into 05 groups (n=10/group): a) Control Group (CG) b) High Fat Group (HG); C) Resveratrol Group (RG) (15mL resveratrol solution 4%/animal/day); D) Grape Juice Group (JG) (15mL/animal/day); E) Red Wine Group (WG) (10mL/animal/day); HG, RG, JG and WG received a high fat diet (20%). The animals performed a treadmill running protocol, speed 10m/min for 10 minutes, 5 days/week, for 60 days. After, they were anesthetized; CM and SM were removed for PCR analysis. Results were expressed as mean ± standard deviation. ANOVA one way and Tukey as post test were performed, and a p < 0.05 was considered significant. Results: FNDC5 on CM: RG = 2,0 ± 0,8; JG = 2,1 ± 0,43 and WG = 1, 7 ± 0,5 displayed higher expression than CG = 0, 7 ± 0,4. FNDC5 on SM: JG = 1, 6 ± 0,6 displayed higher expression when compared to CG = 0, 63 ± 0, 2. UCP2 on CM: RG = 0,4 ± 0,1 and WG = 0, 4 ± 0,27 lower expression when compared to CG = 0, 8 ± 0, 26. UCP2 on SM: RG = 1, 9 ± 1, 4; JG = 2, 4 ± 1, 7 e WG = 2, 7 ± 0, 8 presented greater expression when compared to CG = 0, 5 ± 0, 4. Conclusion: Polyphenol-rich beverages associated with exercise were able to modulate FNDC5 and UCP2 genes expression in CM and SMIntroduction: Diets high fat can lead to obesity and chronic non-communicable diseases. Genes related to thermogenesis regulation may be a possibilty to obesity and its comorbidities prevention. Objective: Evaluate grape juice, red wine and resveratrol and exercise effects, in gene expression modulation of FNDC5 and UCP2 in cardiac (CM) and skeletal (SM) muscles of Wistar rats. Method: Rats Wistar, 90 days, 230g, divided into 05 groups (n=10/group): a) Control Group (CG) b) High Fat Group (HG); C) Resveratrol Group (RG) (15mL resveratrol solution 4%/animal/day); D) Grape Juice Group (JG) (15mL/animal/day); E) Red Wine Group (WG) (10mL/animal/day); HG, RG, JG and WG received a high fat diet (20%). The animals performed a treadmill running protocol, speed 10m/min for 10 minutes, 5 days/week, for 60 days. After, they were anesthetized; CM and SM were removed for PCR analysis. Results were expressed as mean ± standard deviation. ANOVA one way and Tukey as post test were performed, and a p < 0.05 was considered significant. Results: FNDC5 on CM: RG = 2,0 ± 0,8; JG = 2,1 ± 0,43 and WG = 1, 7 ± 0,5 displayed higher expression than CG = 0, 7 ± 0,4. FNDC5 on SM: JG = 1, 6 ± 0,6 displayed higher expression when compared to CG = 0, 63 ± 0, 2. UCP2 on CM: RG = 0,4 ± 0,1 and WG = 0, 4 ± 0,27 lower expression when compared to CG = 0, 8 ± 0, 26. UCP2 on SM: RG = 1, 9 ± 1, 4; JG = 2, 4 ± 1, 7 e WG = 2, 7 ± 0, 8 presented greater expression when compared to CG = 0, 5 ± 0, 4. Conclusion: Polyphenol-rich beverages associated with exercise were able to modulate FNDC5 and UCP2 genes expression in CM and SMRats Wistar, 90 days, 230g, divided into 05 groups (n=10/group): a) Control Group (CG) b) High Fat Group (HG); C) Resveratrol Group (RG) (15mL resveratrol solution 4%/animal/day); D) Grape Juice Group (JG) (15mL/animal/day); E) Red Wine Group (WG) (10mL/animal/day); HG, RG, JG and WG received a high fat diet (20%). The animals performed a treadmill running protocol, speed 10m/min for 10 minutes, 5 days/week, for 60 days. After, they were anesthetized; CM and SM were removed for PCR analysis. Results were expressed as mean ± standard deviation. ANOVA one way and Tukey as post test were performed, and a p < 0.05 was considered significant.
Results: FNDC5 on CM: RG = 2,0 ± 0,8; JG = 2,1 ± 0,43 and WG = 1, 7 ± 0,5 displayed higher expression than CG = 0, 7 ± 0,4. FNDC5 on SM: JG = 1, 6 ± 0,6 displayed higher expression when compared to CG = 0, 63 ± 0, 2. UCP2 on CM: RG = 0,4 ± 0,1 and WG = 0, 4 ± 0,27 lower expression when compared to CG = 0, 8 ± 0, 26. UCP2 on SM: RG = 1, 9 ± 1, 4; JG = 2, 4 ± 1, 7 e WG = 2, 7 ± 0, 8 presented greater expression when compared to CG = 0, 5 ± 0, 4. Conclusion: Polyphenol-rich beverages associated with exercise were able to modulate FNDC5 and UCP2 genes expression in CM and SM

Cite this Article: da SF Fiochi R, Cardoso LMF, da MA Pimenta N, Mota BF, Monnerat JAS, et al. Grape Juice, Red Wine, Resveratrol and Exercise, In the Expression of FNDC5 and UCP2 in Cardiac and Skeletal Muscles of Wistar Rats Submitted To High-Fat Diet. SRL Nutr Food Sci. 2017; 3(1): 001-004.

Published: April 20, 2017

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