Volume 4 Issue 3

Case Report: Primary Amenorrhea after Sex-Mismatched Allogeneic Hematopoietic Stem Cell Transplantation: a Case Report and Literature Review

Tianji Liao1,2#, Li Xiao1,2, Minjin Wang3, and Wei Huang1,2#*

A female patient with primary amenorrhea and 46 XY karyotype can be commonly diagnosed as Y chromosome-related Disorders of Sex Development (DSD) by physicians, which may be not always a correct diagnosis. An 18-year-old girl was evaluated for her primary amenorrhea. Her karyotyping analysis revealed 46 XY. She was diagnosed as aplastic anemia and treated with sex-mismatched allogeneic hematopoietic stem cell transplantation donated from her father when she was ten years old. We finally detected this patient's personal identification was a female by her hair follicle samples, which indicated that DSD was an inappropriate diagnosis for her. Her menstruation presented regularly after we prescribed estrogen-progestin regimen for her. The aim of this case report was to improve the understanding of diagnosis, workup, and treatment of this special primary amenorrhea in the general gynecology practice.
Keywords: Primary amenorrhea; Allogeneic hematopoietic stem cell transplantation; Hair follicle; Primary ovarian insufficiency

Cite this Article: Huang W, Liao T, Xiao L, Wang M. Primary Amenorrhea after Sex-Mismatched Allogeneic Hematopoietic Stem Cell Transplantation: a Case Report and Literature Review. Int J Case Rep Short Rev. 2018;4(3): 040-043.

Published: 08 October 2018

Letter to Editor: Bilateral Tap Block for Postoperative Analgesia in Bladder Augmentation Surgery

Manpreet Singh*, Raksha Kundal and Gunjan Bansal

We report a case of 10 year old female child weighing 21 kg with neurogenic bladder with hydroureteronephrosis (L > R) with L5 spina bifida, lumbar and sacral scoliosis, hydromelia at C3-C7 and syringomyelia D3 and L1 level with hypertension on T. Amlodipine 2.5 mg OD. Neurogenic Bladder Sphincter Dysfunction (NBSD) can develop as a result of a lesion at any level in the nervous system, including the cerebral cortex, spinal cord, or peripheral nervous system [1].

Cite this Article: Singh M, Kundal R, Bansal G. Bilateral Tap Block for Postoperative Analgesia in Bladder Augmentation Surgery. Int J Case Rep Short Rev. 2018;4(3): 038-039.

Published: 31 August 2018

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