Volume 1 Issue 1

Research Article: Treatment of Olive Mill Effluent by Nano-Zinc Oxide-Magnetite

Delia Teresa Sponza1* and Merve Balaban2

Olive Mill Wastewater (OMW) contains high concentration of organic matter, acidic pH values, suspended solids and high content of phenols and polyphenols which are toxic substances. The aim of this study is the removals of COD, total phenol, Total Solid (TS), total nitrogen, total phosphorus and polyphenols (caffeic acid, tyrosol and hydroxytyrosol) in the OMW by Nano-ZnO-Magnetite composite via adsorption and photocatalytic degradation. The specific objectives of this study are to determine the optimum Nano-ZnO-Magnetite concentration, to evaluate effect of time and pH on the treatment of OMW pollutants for maximum removal of pollutants, and to investigate the recovery of composite.
For photocatalytic degradation under UV, the optimum concentration of Nano-ZnO-Magnetite, irradiation time and pH was determined as 3 gram per liter, 30 minute and 4, respectively. The maximum removal efficiencies of COD, total phenol, TS, total nitrogen and total phosphorus were found as 80, 75, 70, 97 and 85 percent, respectively. And also, the maximum removal efficiencies of caffeic acid, tyrosol and hydroxytyrosol were found as 80, 80 and 51 percent, respectively at Nano-ZnO-Magnetite concentration of 3 gram per liter, at irradiation time of 30 minute and at a UV power of 300 W. When we used the same Nano-ZnO-Magnetite for fifth times for treatment of OMW, the COD, phenol and TS removal efficiencies decreased from 80 to 52 percent, from 75 to 48 percent and from70 to 56 percent, respectively. The total cost to treat 1 liter of raw OMW under UV light was 1.09 ∉.
Keywords: Nano-ZnO-Magnetite; Olive mill effluent; Treatment

Cite this Article: Sponza DT, Balaban M. Treatment of Olive Mill Effluent by Nano-Zinc Oxide-Magnetite. Am J Nanotechnol Nanomed. 2018; 1(1): 028-042.

Published: 26 June 2018

Research Article: Multifunctional Core/Shell Hybrid Fe3O4@TiO2@ZIF-8 Nanoparticles as a pH-responsive Vehicle Advances in Targeted Cancer Therapeutics

Minchao Liu1,2#, Yuna Qian1#, Zaian Deng1, Ping Zhao2* and Jianliang Shen1,3*

It is widely accepted that an ideal targeted drug delivery system would be directed to the tumor tissue and selectively release therapeutic molecules. In this study, we have developed a ZIF-8 coated magnetic nano delivery system named Fe3O4@TiO2@ZIF-8. Because of the Fe3O4 magnetic core, the drug delivery vehicle provides targeting of drugs to the tumor site under a magnetic field. Owing to the porosity and acid-sensitivity of zeolitic imidazolate framework-8 (ZIF-8), Fe3O4@TiO2@ZIF-8 NPs not only displayed an improved drug loading capacity compared to most of the inorganic nanocarriers, but also exhibited excellent pH-triggered release of Daunomycin (DNM) in vitro. Co-incubation of Hela cells with hybrid NPs shows low toxicity and rapid cellular endocytosis, consequently displays enhanced the inhibition of cancer cell growth by DNM. These results provide convincing evidence establishing the multifunctional Fe3O4@TiO2@ZIF-8 NPs as promising candidates for tumor therapy.
Keywords: Daunomycin; Superparamagnetic iron oxide nanoparticle; Magnetic targeted drug delivery; Zeolitic imidazolate framework-8; pH-triggered release

Cite this Article: Liu M, Qian Y, Deng Z, Zhao P, Shen J. Multifunctional Core/Shell Hybrid Fe3O4@TiO2@ZIF-8 Nanoparticles as a pH-responsive Vehicle Advances in Targeted Cancer Therapeutics. Am J Nanotechnol Nanomed. 2018; 1(1): 016-027.

Published: 16 June 2018

Research Article: A Performance Comparison of Graft Copolymer Hydrogels Based on Functionalized-Tragacanth Gum/Polyacrylic Acid and Polyacrylamide as Antibacterial and Antifungal Drug Release Vehicles

Javid Monjezi1*, Rezvan Jamaledin1,2, Mousa Ghaemy3, Arash Moeini2 and Pooyan Makvandi3,4*

The present article deals with design of antibacterial and antifungal pH-responsive hydrogels based on Quaternary Ammonium Functionalized-Tragacanth Gum (QTG) biopolymer as drug delivery systems. The antimicrobial effects of the graft-copolymer hydrogels QTG/ polyacrylic acid (QTG-AA) and QTG/polyacrylamide (QTG-AM) were investigated against five standard microorganisms including Candida albicans, Escherichia coli, Bacillus subtilis, Staphylococcus aureus, and Pseudomonas aeruginosa. The results of the in-vitro release of quercetin as a drug from the functionalized copolymer hydrogels exhibited dependence on the pH, immersion time, medium, and temperature. All copolymer hydrogels demonstrated antibacterial and antifungal properties and moreover, QTG-AM copolymers presented higher antimicrobial activity than QTG-AA copolymers.
Keywords: Release profile; Antibacterial; Drug release; Antimicrobial; Antifungal

Cite this Article: Monjezi J, Jamaledin R, Ghaemy M, Moeini A, Makvandi P. A Performance Comparison of Graft Copolymer Hydrogels Based on Functionalized-Tragacanth Gum/Polyacrylic Acid and Polyacrylamide as Antibacterial and Antifungal Drug Release Vehicles. Am J Nanotechnol Nanomed. 2018; 1(1): 010-015.

Published: 21 May 2018

Editorial: Biomedical Instrumentation and Applications of Biospectroscopic Methods and Techniques in Malignant and Benign Human Cancer Cells and Tissues Studies under Synchrotron Radiation and Anti-Cancer Nano Drugs Delivery

Alireza Heidari*

In the current study, we have experimentally and comparatively investigated and compared malignant human cancer cells and tissues before and after irradiating of synchrotron radiation using Small-Angle X-Ray Scattering (SAXS), Ultra-Small Angle X-Ray Scattering (USAXS), Fluctuation X-Ray Scattering (FXS), Wide-Angle X-Ray Scattering (WAXS), Grazing- Incidence Small-Angle X-Ray Scattering (GISAXS),

Cite this Article: Heidari A. Biomedical Instrumentation and Applications of Biospectroscopic Methods and Techniques in Malignant and Benign Human Cancer Cells and Tissues Studies under Synchrotron Radiation and Anti-Cancer Nano Drugs Delivery. Am J Nanotechnol Nanomed. 2018; 1(1): 001-009.

Published: 28 March 2018

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