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Case Report: Colonic Metastasis with Epidermal Growth Factor Receptor Mutation from Primary Lung Adenocarcinoma: a Case Report and Review of the Literature

Chun C. Chang*, Ya L. Chen, Chih J. Chen, Woei H. Chai and Ming T. Lin

Colon cancer with lung metastasis is very common clinically, but lung cancer with colon metastasis is relatively rare. More than half of lung cancers have distant metastasis at the time of the initial diagnosis. Despite patients undergoing resection for potential cure of lung cancer, silent metastatic disease is also considered. Gastrointestinal metastasis had rarely been reported, whereas colonic metastasis seems to be particularly rare. Although the majority of reported patients lack abdominal symptoms, we need to be aware of gastrointestinal metastasis in lung cancer patients who have gastrointestinal symptoms. This report presents a clinical case with colonic metastasis with Epidermal Growth Factor Receptor (EGFR) Mutation from primary lung adenocarcinoma. Immunohistochemistry and molecular genetics can provide important information in the practice of clinical medicine.
Keywords: Lung cancer; Colon metastasis; Epidermal Growth Factor Receptor (EGFR) Mutation.

Cite this Article: Chang CC, Chen YL, Chen CJ, Chai WH, Lin MT. Colonic Metastasis with Epidermal Growth Factor Receptor Mutation from Primary Lung Adenocarcinoma: a Case Report and Review of the Literature. Scientific Journal of Pathology & Research. 2017;1(1): 001-004.

Published: 12 May 2017

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