Volume 1 Issue 1
Early explorations into the workings of the immune system have generally taken a reductionist approach. Analysis of the role of cellular subsets in the immune response focused on the interactions of two cells types in culture. Similarly, in order to understand the function of a particular protein, it was isolated, expressed and analyzed in vacuo. The introduction of mass spectrometry allowed for the analysis of in situ protein abundance, interactions and post-translational modifications, yet dynamic interactions were still beyond reach of this powerful technique.
Cite this Article: Spencer C. Immunoproteomics: from Reductionist to Systems Immunology. Int J Proteom Bioinform. 2016;1(1): 001-002.
Published: 03 January 2016
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